Uripan XR for the relief of symptoms of the bladder instability associated

 
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Uripan XR®
Oxybutynin Hydrochloride
10 mg Extended Release Tablets

Composition :

Uripan XRe(oxybutynin Hydrochloride) is an antispasmodic and
anticholinergic agent. Each Uripan XR· Extended Release Tablet
contains 10 mg of oxybutynin USP, formulated as a once-a-day
controlled – release tablet for oral administration.

Properties :

Uripan XRe (Oxybutynin) has pharmacological properties similar to
some anticholinergic, antispasmodic, local anesthetic and antihistaminic compounds. It exerts anti muscarinic effect significantly less than that of atropine but its antispasmodic activity is considerably greater than atropine, producing an effect on the detrusor muscle 4 to 10 times that of atropine.
Unlike papaverine it does not appear to affect the smooth muscles of
the blood vessels. It is believed that Uripan XR· suppresses the urge
to void by increasing the bladder capacity secondary to the relaxation of the bladder smooth muscles and a corresponding reduction in the number of contractions ofthe detrusor muscles.

Indications :

Uripan XR is indicated for the relief of symptoms of the bladder
instability associated with voiding in patients with neurogenic bladder
I.e. : urgency, frequency, leakage, incontinence and dysuria

Dosage & administration :

Adults: Uripan XR·(oxybutynin Hydrochloride) is a once-daily
Extended-release tablet. It is recommended not to exceed 2 tablets
Children above 5 years & older: 1 tablet once daily.

Contraindications :

Uripan XRe(oxybutynin chloride) is contraindicated in patients
with intestinal obstruction, toxic megacolon, severe ulcerative colitis, closed angle glaucoma, myasthenia gravis and urinary obstruction. Uripan XR” is also contraindicated in patients who have demonstrated hypersensitivity to the drug substance or other
components of the product.

Adverse reactions :

Most adverse reactions encountered with oxybutynin administration are due to its anticholinergic and antispasmodic activity. These effects include dizziness, flushing, confusion clumsiness and palpitations. Transient blurred vision, urticaria, constipation, xerostomia and anhidrosis are also rarely reported side effects.

Warning & Precautions :

It should be administered cautiously to patients with coronary
arteries diseases, congestive heart failure, cardiac arrhythmias and
hypertension, autonomic neuropathy, hepatic disease or renal
diseases. It should also be taken cautiously with drugs having
anti muscarinic properties, CNS-depressants parasympatholytics,
ketoconazole and opiate agonists. Its use during pregnancy & breast
feeding has not been established.

Storage :

Store below 30’C & protect from direct sunlight, keep out of reach of
children.

Pack :

Box of two strips each containing 10 extended release tablets.

Manufactured by :

ADWIA Co. S.A.E 10″ of Ramadan City Egypt

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