Cipazole forte anti protozoal drug for intestinal amebiasis and giardiasis

Cipazole forte
Anti-Protozoal Drug

Composition:

Each tablet contains:

Secnidazole               1 gm

Properties and Mechanism of Action:

Cipazole forte contains Secnidazole which belongs to Nitroimidazole derivatives.
It is an anti-protozoal drug which has pharmacological activity against Intestinal and
Hepatic Amebiasis, Giardiasis and Trichomonas vaginalis.
** Recent studies showed that a single 1 gm oral dose of Secnidazole is effective to
cure bacterial vaginosis associated with Gardnerella vaginalis.

Indications and Usage:

Cipazole forte is indicated for the treatment of:
– Intestinal Amebiasis.
– Hepatic Amebiasis.
– Giardiasis.
– Urethritis and vaginitis due to Trichomonas vaginalis.

Contraindications:

Cipazole forte is contraindicated in:
– Patients with known hypersensitivity to Imidazole derivatives.
– Pregnancy and Lactation.

Side Effects:

– Digestive disorders with abdominal pain, change in taste, glossitis, stomatitis.
– Urticaria, moderate leukopenia, reversible upon withdrawal of treatment.

Drug-Drug Interactions:

Alcoholic drinks and alcohol containing medicines should be avoided during
Secnidazole treatment.

Precautions:

• Do not administer to patients with a history of blood dyscrasias.

Dosage and Administration:

– Acute Intestinal Amebiasis: One-day treatment
Adults: 2 gm (2 tablets) as a single dose.
Children: 30 mgl kg as a single or several divided doses.
– Hepatic Amebiasis: Five-day treatment;
Daily dose:
Adults: 1.5 gm (one and a half tablets) as a single dose.
Children: 30 mgl kg as a single or several divided doses.
– Urogenital Trichomoniasis:
2 gm (2 tablets) as a single dose.
* The dose preferably be taken during a meal.

How Supplied:

A box containing one blister of 2 tablets.

Produced by :

SIGMA Pharrnaceutical industries -Egypt- S.A.E.