Farcocin for primary skin infections and secondary skin infections

Farcocin
 
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 FARCOCIN
Cream \ Ointment

Company Name:

Pharco Pharmaceuticals

Trade Name:

Farcocin (Cream & Ointment)

Generic Name:

Gentamicin sulphate

Composition:

Each 1 9 of the cream or ointment contams:
Gentamicin sulphate equivalent to 1 mg gentamicin activity

Pharmaceutical Form:

Cream or Ointment

Pharmacological Action:

Farcocin cream and Farcocin ointment (gentamicin) are highly effective formulations for topical treatment of primary and secondary skin mfections caused by gentamicin-sensitive pathogenic bactena. Farcocin is bactericidal against most strains of staphylococci (including penicillin-resistant strams), some strains 01 streptococci and the Gram-negative bacteria: Pseudomonas aerugmosa (insensitive to many antibiotics). Escherichia coli and klebsiella, Proteus, Enterobacter, Citrobacter
and Serratia species. Gentamicin (an aminoglycoside antibiotic) binds irreversibly to tle 30S ribosomal subunits causing inhibition of bacterial protein synthesis and induces misreac.mg of the genetic code with eventual bacterial cell death. Farcocin is formulated in cream and 0 ntment forms to suit the different coromons of infected skin. The cream suits hairy and intertrigmous areas and is recommended for wet oozing and greasy infected skin while the ointment IS preferable for infections
of dry eczematous or psoriatic skin.

Pharmacokinetics:

Systemic absorption of gentamicin has been reported after topical use on denuded skin and burns and following instillation into the imgation of wounds.

Indications:

Skin infections caused by gentamicin-susceptible bacteria including :
Primary skin infections: Impetigo contagiosa, furunculosis, ecthyma, superficial folliculitis, sycosis barbae and pyoderma gangrenosum .
Secondary skin infections: infected wounds and skin ulcers, infected superficial burns, infectious eczematoid dermatitis, Infected seborrheic and contact derrnatitrs, pustular acne, pustular psoriasis, infected insect bites and stings, paronychia and bacterial supennfection.

Mode of use:

A thin film of Farcocin cream or Farcocin ointment is applied to cover completely the affected skin area. Application is repeated 3to 4 times daily. The treated area may be covered with C3: gauze dressing if needed.

Contra indications :

Hypersensitivity to gentamicin.

Side effects:

Treatment with gentamicin may produce transient irritation (erythema and pruritus) that usually did not require discontinuance of treatment.

Drug Interactions:

None reported while using Gentamicin topically.

Pregnancy & lactation:

Since safety of the use of Farcocin Cream/Ointment in pregnant woman has not absolutely established, il should be used under medical supervision and it should not be used in pregnant patients in large amounts or for prolonged periods of time.
Since it is not known whether gentamicin is excreted in the human milk, caution should be exercised when administering to a nursing woman.

Warnings & Precautions:

Use of topical antibiotics occasionally allows the overgrowth of nonsusceptible organisms, including fungi. If this occurs, or if irritation, sensitization or superinfection develops, treatment with qentamicin should be discontinued and
appropriate therapy Instituted. Systemic absorption of topically applied gentamicin may be Increased if extensive body suriace areas are treated, especially over prolonged time periods or in the presence of dermal disruption. In these cases, the undesirable effects which occur following systemic use of gentamicin may
potentially occur. Cautious use is recommended under these conditions, particularly in infants and children. Farcocin Cream/Ointment is not for ophthalmic use.

Packing:

Union of Arab Pharmacists.
Cream: A tube containing 15 or 20 gm.
Ointment: A tube containing 20 gm.

Storage:

Store at temperature 15 ·300 C.
Keep out of the reach of children.

produced by :

pharco pharmaceuticals alexandria

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