URICOL Effervescent Granules
Urinary Antiseptic, Antispasmodic & For Urinary Lithiasis
Each sache1 (5 g) contains:
Hexamine 500.00 mg
Piperazine citrate 190.00 mg
Khellin 1.83 mg
Effervescen1 base 10 5.00g
URICOl is a multifunctional formulation combining three active ingredients, each complementing the other wi1h potent urinary antiseptic, antispasmodic and anlililhic effects. Hexamine, the first il1!)redienl in URICOL, is an antiseptic that prevents and treats urinary tract infections and asymptomatic bactenuria. In acidic urine, hexamine is hydrolyzed to formaldehyde which exerts potent antimicrobial effect against Gram-positive and Gram-negative bacteria and fungi. Hexamine is safe for lOng-term use and no emergence of resistance occurs. Piperazine citrate, the second ingredient in URICO’L, adjusts the pH of urine to the appropriate value that helps dissolve uric acid and prevents formation and deposition of urate calculi. Khellin, the third ingredient in
URICOL, is a powerful antispasmodic that relieves urinary smooth muscle spasm and hypermotility associated with infection, diagnostic procedures or irritations due to calculi. These properties demonstrate the superior antiseptic effects of URICOL and its h~h efficacy in relievir19 and overcoming urinary tract spasm, and reventing formation and deposition of unnary calculi. FormulatIOn of URICOL in single dose (5 g) sachets, ensures pleasant taste and rapid absorption with fast onset of action.
– Chronic urinary tract infections, as in pyelitis, pyelonephritis, cystitis and infections accompanying neurogenic bladder.
– As a prophylaxis against urinary tract infection in patients with residual urine due to different causes including neuroloical ctseasss.os-proonqed bladder catheterization.
– fast relif of urinary tract spasms and irritations caused by crystalluria and urinary calculi
– Prevention of urinary tract lithiasis.
Dosage and mode of administration:
The contents of one URICOL sachet is added to half a glass of water and taken during effervescence.
Chronic urinary tract infections, spasms of the urinary tract and prevention of urinary tract lithiasis: 1-2 sachets to be taken 3 – 4 times daily or as directed by the physician.
Hypersensitivity to any component of URICOL, severe hepatic diseases and renal insufficiency.
Hexamine containing prepartions should not be given to patients
taking sulfonamides to avoid formation of insoluble precipitates in urinary tract
Side effects :
URICOL is safe and well tolerated with almost no side effects However nausea, stomach upset Of rash might rarely occur.
pregnancy and lactation :
medications containing hexamine should be taken under medical .
supervision during pregnancy and lactation.
Concomitant ad.mlnistratiOn of hexamine with sulfonamides results In mutual antagomsm.
Interference with laboratory tests:
Overdosage and treatment :
None reported with effervescent formulations.
A box containing 6 or 12 sachets (5 9 each).
keep at tempera1ure (15· 3o C), away from moisture.
Keep oul of Ihe reach of children.
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